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January to March 2020 | Vol. 13 | Issue 1 | 06-10
Antisense Oligonucleotides: Adding Sense to Therapeutic Medicine
A Haseena, Amita Moirangthem, Shubha R Phadke
Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Address for Correspondence Email: amis.72000@gmail.com
Rapid progress in the field of molecular biology has led to the development of numerous genetic therapies. Among these, antisense oligonucleotide (ASO) therapeutics have recently gained momentum due to their application in the spectrum of disorders ranging from neurodegenerative disorders to malignancies. This brief review discusses the principle of ASO based therapies, mechanism of action and their current role in the field of therapeutic medicine.
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