Contributed by: Anju Shukla  
  An 8-years-old girl had clinical features of cloverleaf skull, telecanthus, midface
retrusion, brachydactyly, cutaneous syndactyly, postaxial polydactyly, broad
thumbs and great toes with normal intelligence and presence of
brachymesophalangy on radiography. Identify the condition.

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Answer to PhotoQuiz 27
Congenital Contractural Arachnodactyly
Congenital Contractural Arachnodactyly (Beals syndrome; OMIM #121050) is a rare
autosomal dominant connective tissue disorder caused by mutation in FBN2 (Fibrillin-2)
gene. It is characterized by a Marfanoid habitus, contractures, arachnodactyly, scoliosis,
crumpled ears and rarely aortic dilatation.
Correct responses were given by:
1. Girish Subramaniam, Nagpur
2. Prashanth Verma, Saudi Arabia
3. Rekha Goyal, Jaipur
4. Niby J Elackatt, Bengaluru
5. Beena S, Chennai
6. Ravi Goyal, Kota, Rajasthan