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Volume 4 | Issue 1 | January to March 2011

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January to March 2011 | Vol 4 | Issue 1 | Pages 1-2
Ten classes in Medical Genetics and 'more to come..
I am very happy to write this editorial for the eleventh issue of 'Genetic clinics' came into existance in july 2008 and has been regularly published every three months. In each isuue of the newsletter an attempt is made to cover various and latest topics which would interest clinicians and geneticists...

Shubha R Phadke
July-September 2011 | Vol 4 | Issue 3 | Pages 3-6
Molecular Cytogenetics Illustrated: SKY and FISH
Traditional chromosomal analysis was the mainstay of cytogenetic investigations until the advent of molecular cytogenetics. The molecular cytogenetic techniques have revolutionized the practice of cytogenetics. The resolution of analysis has increased from 10MB for chromosomal analysis to just a few base pairs...

Usha R Dutta, Vijay Kumar Pidugu, Ashwin B Dalal
July-September 2011 | Vol 4 | Issue 3 | Pages 7-12
Too Dense Bones: Too Many Genes!
Bone is vital tissue which not only provides support to our bodies, but is also important for hematopoiesis and maintainance of mineral homeostasis. The density of bones is an exquisitely regulated phenomenon. Various hormones, local trophic factors and enzymes govern bone formation and breakdown by their actions through...

Shagun Aggarwal, Shubha R Padke
July-September 2011 | Vol 4 | Issue 3 | Pages 13
Long term efficacy of gene therapy.....
Abina et al have reviewed the long term outcome after gene therapy in nine patients with x-linked severe combined immunodeficiency (SCID-X). Nine patients who underwent ex-vivo retrovirus-mediated transfer of gamma chain to autologous CD34+ bone marrow cells between 1999 to 2002 were assessed. Of these, 8 patients were alive after a median follw up period of nine years..

Girisha KM